Some patients went to the hospital from the early pain and numbness, but after treating the symptoms for a little relief, it didn’t take long for them to relapse and worsen, and finally a diabetic foot ulcer appeared, which was treated in the hospital for a long time without getting better. In fact, there is a process from mild to severe diabetic foot, and each process will definitely make the patient better if we find the cause of the disease and treat it symptomatically. At the beginning, the blood glucose may not be well controlled, fluctuating greatly, combined with blood pressure and lipid abnormalities, etc. As the disease lengthens, one complication after another will begin to appear. These include neuropathy, which can easily cause wounds, and peripheral vascular disease, which can affect wound healing; in addition, poor blood sugar control can also affect the function of the immune system and induce infection, and finally induce diabetic foot. Because of neuropathy, many patients do not feel pain, and because the infection has not spread throughout the body at the beginning of the disease, there are no symptoms such as fever, which makes many patients with diabetic foot infections feel that it is normal. There is because of the vascular lesion, the wound does not get enough blood, nutrients and medication, and the wound will worsen. In many cases, the patient is not brought to the hospital until the symptoms become severe or are discovered by a close family member. By this time, the wound may have spread for weeks or even months, allowing the infection to rage for so long that doctors often find it quite difficult. Chronic wound infection over time, may be from the original local infection slowly spread, began to appear increased wound discharge or subcutaneous abscess. In severe cases, it may also invade deeper into the bone and turn into a chronic osteomyelitis that requires longer treatment. In addition, foot infections often last for weeks or even months, and the strains of infection are even more complex and unpredictable. They range from Gram-positive bacteria such as Staphylococcus aureus, which are common in skin infections, to more virulent Gram-negative bacteria such as Pseudomonas aeruginosa, and even anaerobic bacteria that can cause wounds to smell badly. In addition, according to our cases, diabetic foot patients are often prone to other health problems, such as stroke, coronary heart disease or diabetic nephropathy, which can lead to aggravation of the diabetic foot and definitely make treatment more difficult. Finding the cause and treating it is the key. But there is a problem, from above diabetic foot is a multidisciplinary problem, heart, kidney, brain, etc., medical, surgical, neurological and many others, so the treatment is definitely not a job that a single department can do, but requires a multidisciplinary joint diagnosis and treatment model, where doctors from different fields participate in the treatment together to develop a personalized treatment plan, especially the combined Chinese and Western medicine model, which can effectively improve the patient’s physical condition and improve the speed of wound healing and achieve the purpose of non-amputation treatment.