Lumbar spine tuberculosis does not have a fast-acting drug, you can choose anti-tuberculosis drugs according to the condition, in accordance with the principle of early, adequate amount, full course of joint application, commonly used anti-tuberculosis drugs are isoniazid, rifampicin, ethambutol and so on. 1. Isoniazid: Isoniazid treatment for lumbar spine tuberculosis is mainly applicable to the consolidation period, belonging to the anti-tuberculosis drugs, which can stabilize the condition and reduce the harm brought by the disease. 2. Rifampicin: Rifampicin is also suitable for the consolidation period, and is currently advocated to be used in combination with isoniazid, so as to control the development of lumbar spine tuberculosis. 3. Ethambutol: Ethambutol is effective in the treatment of lumbar spine tuberculosis and can promote the recovery of lumbar spine function as soon as possible, and at the same time improve lumbar pain, spinal deformity and other discomforts, which is suitable for the consolidation period, and it can be used in combination with isoniazid. Lumbar spine tuberculosis medication should be used in strict compliance with the doctor’s instructions, it is recommended that patients go to the hospital in a timely manner to check the cause of the disease, timely treatment, and regular review, do not take medication, so as not to lead to adverse consequences.