Frostbite on the face of infants can be treated with oral vasodilator drugs, such as niacin, under the supervision of a doctor, and appropriate topical medications according to the pattern of the rash. For those who are not broken can apply vitamin E ointment, or 10% camphor ointment, 2 times a day for treatment. For those with ulcers, boric acid and zinc oxide oil, or erythromycin ointment can be applied twice a day to strengthen the anti-inflammatory and anti-infective treatment. At the same time can also be used with the application of recombinant bovine alkaline fibroblast growth factor gel for application, can play a role in antibacterial and anti-inflammatory, promote wound healing and growth of the therapeutic purpose. It can also be combined with audio electrotherapy and helium-neon laser for physical irradiation treatment.