The treatment of gynecomastia needs to be rationally chosen according to the cause of the disease, the size of the breasts, the presence or absence of accompanying symptoms and general conditions, and is categorized into treatment of the cause of the disease, drug treatment and surgical treatment. 1. Etiological treatment: Gynecomastia caused by drugs and tumors should be treated in time, including stopping the use of estrogenic drugs such as estradiol, and removing tumors in the case of male breast cancer, etc. Generally speaking, after stopping the drugs or controlling the primary disease, the accompanying symptom of abnormal breast development can disappear gradually. 2. Drug treatment: including letrozole, anastrozole and other aromatase inhibitors, which can reduce the production of estrogen in the body. 3. For breast development that seriously affects aesthetics or causes psychological impact, primary breast enlargement that has lasted for more than 2 years at the age of 17~20 or for more than 1 year at the age of 20 or above, secondary breast enlargement that has not subsided for more than 1 year after cure of the primary disease or discontinuation of medication, and suspected malignant changes, surgical treatments such as open mastectomy, liposuction, and lumpectomy are needed. In addition, physiological enlargement of the breasts can occur during puberty due to the secretion of physiological sex hormones, which does not require intervention. When breast development occurs, it is recommended to go to the hospital in time. The above medications should be used under the guidance of a clinician and unauthorized use is prohibited.