When blisters appear after cryotherapy, which is clinically known as blisters, it is generally not recommended to poke them to prevent infection. Generally speaking, blisters after cryotherapy is a normal phenomenon, and the blisters will be absorbed by themselves and return to normal, during this period, you can use iodine pomade and other appropriate disinfection, no need to carry out special treatment, and pay attention to avoid friction, scratching can be. If the blisters are particularly large or seriously affect the daily life, it is not recommended to pick them by yourself, because improper operation may easily cause infection in the area and further aggravate the related symptoms. At this time, it is recommended to go to the hospital, by the doctor in a sterile environment to carry out the relevant operations, the blisters for treatment, and under the guidance of the doctor oral antibiotics such as clindamycin, regular change of disinfection, etc., can effectively avoid the occurrence of infection.