Toothache is usually possible when you want to have nerve killing treatment, also known as root canal treatment, during the acute painful period. If the toothache is caused by pulpitis or periapical inflammation, the best treatment is root canal therapy. Root canal treatment is performed during the acute painful period, with the application of local anesthesia. In case of acute pulpitis, if the anesthetic is injected near the nerve of the tooth, the painful symptoms will disappear immediately and the pain will not appear again during the treatment. However, if the toothache is caused by decay or the presence of jawbone tumor in the apical part of the tooth, it is not necessary to perform nerve killing treatment, and it is necessary to perform filling treatment surgery on the decayed tissue and incision of the tumor in the jawbone.