Elderly people with knee pain are firstly recommended to undergo local examination, including blood routine, blood sedimentation, anti-O, rheumatoid factor and other tests, followed by the need to pay attention to whether it is due to injury. The drugs used in this group of patients include the following categories: 1. symptom-improving drugs: the first subcategory is acetaminophen, an antipyretic and analgesic, and its adverse effects are mild, and the maximum daily dose is 4000 mg. the American College of Rheumatology lists acetaminophen, or paracetamol, as the drug of choice for the treatment of osteoarthritis; the second subcategory includes non-steroidal anti-inflammatory drugs, nimesulide, meloxicam, rofecoxib, celecoxib, etc., which are routinely used, Celecoxib, etc., are routinely used. Inhibit the synthesis of prostaglandins by inhibiting cyclooxygenase, thus preventing the destruction of cartilage, which can eliminate joint pain and stiffness, and can inhibit the inflammatory response; 2. Drugs to improve the condition: including glucosamine, which can stimulate cartilage proteoglycan synthesis, reduce the activity of catabolic enzymes, reverse the adverse effects of interleukin-1 on cartilage metabolism, reduce the production of superoxide groups, and increase cartilage-specific type II Diacerein plays an anti-inflammatory and articular cartilage protective role by inhibiting the production of oxygen free radicals, inhibiting metalloproteinase activity and stabilizing lysosomal membranes to improve the course of osteoarthritis; sodium hyaluronate reduces friction on the joint surface and alleviates joint pain; then there is superoxide dismutase, which eliminates inflammation and tissue damage due to macrophages stimulated by peroxides and stabilizes The cytoplasmic membrane of macrophages, blocking the degradation of cartilage collagen, hyaluronic acid and proteoglycan, breaking the vicious cycle of tissue damage and severity; 3. Chinese medicinal preparations: some hospitals make their own Tao Ren Knee Health Pills, Shu Tendon and Blood Pain Relief Cream, etc.