Gout occurs mostly in middle-aged and older men. Middle-aged and older people are often prone to atherosclerosis often accompanied by hypertension when they begin to gain weight. The incidence of diabetes mellitus is also common in middle-aged and elderly people. In obese people, they usually eat too much and consume less; causing excessive fat to accumulate under the skin, in the abdomen or in the internal organs. Whenever exertion, hunger, use the stored fat to generate heat for the body’s activities, then fat “burning” ketone bodies produced by the obstruction of blood uric acid excretion, indirectly make the blood uric acid level increased, and induce gout. Some people believe that obese people, their bodies to insulin resistance prone to diabetes. People with hypertension often use diuretics to control blood pressure, diuresis makes extracellular fluid loss, resulting in increased renal tubular reabsorption of uric acid salts, and long-term hypertension causes sclerosis of the renal arteries, which can lead to a decline in kidney function, reducing blood uric acid excretion, resulting in a relatively high blood uric acid concentration and inducing gout. Some scholars have found that hypertension, diabetes and hyperuricemia have similar genes, and gout and hyperlipidemia have family heredity, and both have insulin resistance syndrome, thus producing disorders of sugar, fat and purine metabolism, making gout, obesity, hypertension and diabetes all in one.