Whether a thyroid nodule of 2.8mm is serious or not needs to be decided according to the nature and location of the nodule, if it is a benign nodule without obvious symptoms, it is generally not serious, if it is a malignant nodule, it is more serious. Thyroid nodule 2.8mm, the patient did not appear other uncomfortable symptoms, and in the process of examination of the thyroid nodule shape is regular, clear boundaries, such thyroid nodule is generally benign than the greater chance, generally not serious, but need to go to the hospital regularly for review. Thyroid nodule 2.8mm, if the patient in the process of examination appeared in the shape of irregular, border is not clear, combined with the phenomenon of calcification, general malignant nodule chances are greater, the patient also need to improve the thyroid puncture examination, a clear diagnosis. If the diagnosis is malignant, it is generally more serious. In the treatment of thyroid nodules, must strictly follow the doctor’s instructions, not blindly use drugs.