The manifestation of fever in children after 13-valent pneumonia vaccination is particularly common in clinical practice and has the following factors: 1. The most common is due to adverse reactions to this vaccine, as fever may occur during the process of vaccine injection into the body to produce antibodies, which generally does not require treatment and can be relieved by itself, and the fever is not too high. 2. Many children injected with the vaccine process is frightened, which can also lead to fever. If the body temperature exceeds 38.5℃, you can choose antipyretic drugs or combine them with physical cooling, and put the baby in a quiet and comfortable environment to relax as much as possible. 3. Upper respiratory tract infections caused by vaccination can lead to fever, which needs to be treated with anti-cold and antiviral drugs. Therefore, in the case of fever after vaccination, it is necessary to further determine what causes it and then treat it symptomatically.