Numbness of the toes may be caused by lumbar spine disease, trauma, lower extremity vascular disease and other diseases. 1. Lumbar spine disease: it is common in degenerative lumbar spine disease or lumbar spine tumor that causes pressure on the nerve roots innervating the lower limbs, and the patient may have symptoms such as numbness of the toes, pain, and limitation of activities. 2. Trauma: due to trauma and other factors acting on the toes, local pain, swelling, causing local epidermal nerve injury, patients may feel localized numbness of the toes. 3. Lower extremity vascular diseases: due to lower extremity vascular diseases such as lower extremity arterial embolism, lower extremity varicose veins and other diseases lead to poor local blood circulation and insufficient blood supply to the nerves, which causes patients to feel abnormal sensations in the toes, numbness and other sensations. There may be other reasons for the numbness of the toes, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment.