After the eradication of H. pylori in atrophic gastritis, symptoms such as abdominal pain and bloating can be relieved. If only gastric mucosal atrophy without intestinal chemosis is present, generally after the eradication of H. pylori, it will take at least 2 weeks for the function of gastric mucosa to start recovering according to the individual’s physique and condition; if gastric mucosal atrophy is accompanied by intestinal chemosis at the same time, it is generally difficult to be completely cured. Atrophic gastritis refers to a chronic gastric disease in which the epithelium of the gastric mucosa suffers repeated damage leading to atrophy of the intrinsic glands, with or without intestinal chemosis and/or pseudo-pyloric glandular chemosis. It is mainly characterized by non-specific dyspeptic symptoms, such as epigastric pain, postprandial fullness and early satiety, loss of appetite, and acid reflux. Eradication of Helicobacter pylori treatment can prevent gastric mucosal atrophy and delay the occurrence and development of intestinal metaplasia to a certain extent. In some patients, gastric mucosal atrophy can be reversed, but intestinal metaplasia is difficult to reverse; some patients with atrophic gastritis also have the possibility of cancer. Patients should consult the doctor in time, make a clear diagnosis, and follow the doctor’s instructions for treatment.