Most patients with dry syndrome have a good prognosis if they actively cooperate with their doctors and take relevant treatment measures. However, if the patient does not follow the doctor’s instructions to standardize the treatment, it may endanger the life and health. Dry syndrome is a chronic inflammatory disease that involves a variety of exocrine glands. Patients may experience symptoms such as dry mouth, dry tongue, dry eyes, dry skin, or muscle pain, dry cough, and diarrhea. Once diagnosed with dry syndrome, patients take treatment in time, generally with a better prognosis, can control the development of the disease, thus improving the prognosis. However, if patients with dry syndrome do not follow the doctor’s instructions to regulate treatment, or treatment is not timely, it may lead to disease deterioration, pulmonary fibrosis, central neuropathy, renal insufficiency and other conditions, life-threatening, and adversely affect the patient’s body. It is recommended that patients with dry syndrome should consult the rheumatology and immunology department in time, and during the treatment period, they should follow the doctor’s instructions for regular review, so as to understand the recovery of the disease. During the treatment period, patients should follow the doctor’s instructions for regular checkups in order to know the recovery of the disease. In the daily life, patients should ensure sufficient sleep, pay attention to personal hygiene, and quit smoking and drinking.