With the development of society, people’s lives are becoming more and more stressful, and many people unknowingly develop bad habits, smoking and alcoholism, which slowly form various diseases. The following is a detailed introduction of the specific causes of the disease, and we hope you will take this as a warning to stay away from the disease and cherish your health. How Stomach Cancer is formed 1. Geographical environment and dietary and living factors Many people have the possibility to have diseases in their lives, especially once cancer occurs, it will be life-threatening. There are obvious geographical differences in the incidence of stomach cancer. The incidence of stomach cancer in the northwest and east coast of China is significantly higher than that in the south. The high incidence of distal gastric cancer among long-term consumers of fumigated and salted foods is related to the high content of carcinogens or former carcinogens such as nitrite, fungal toxins and polycyclic aromatic hydrocarbon compounds in foods; the risk of gastric cancer among smokers is 50% higher than that of non-smokers. 2. Helicobacter pylori infection Some diseases also occur as a result of infection, and you should pay attention to the causes of the diseases in your life. The rate of Hp infection among adults in China’s high incidence area of gastric cancer is over 60%. H. pylori can promote the conversion of nitrate into nitrite and nitrosamine, which can cause cancer; Hp infection causes chronic inflammation of gastric mucosa plus environmental pathogenic factors to accelerate the overproliferation of mucosal epithelial cells, leading to aberration and cancer. 3. precancerous lesions The occurrence of many diseases is through a cancerous change, after all, after the occurrence of disease, patients will have changes in disease. Gastric diseases include gastric polyps, chronic atrophic gastritis and residual stomach after partial gastrectomy. These lesions may be accompanied by chronic inflammatory process of different degrees, intestinal epithelial chemosis or atypical hyperplasia of gastric mucosa, which may transform into cancer. Precancerous lesions refer to pathological histological changes in the gastric mucosa that are prone to cancer, which are junctional pathological changes in the process of transformation from benign epithelial tissue to cancer. Genetic and genetic studies show that the incidence of gastric cancer is 4 times higher in the blood relatives of gastric cancer patients than in the control group. The carcinogenesis of gastric cancer is a multifactorial, multi-step and multi-stage development process, involving changes of oncogenes, oncogenes, apoptosis-related genes and metastasis-related genes, etc., and the forms of genetic changes are also various. Warm Tips: How gastric cancer is formed has been understood. Stomach cancer has no symptoms in the early stage, so patients can easily ignore the treatment, and it will develop into stomach cancer in the late stage.