Phantom limb sensation is the feeling that the amputee still has the presence of that hand or foot after a part of the limb has been amputated, which is a normal phenomenon and the sensation can persist for a long time. Amputation patients experience phantom limb pain because their brains make a misregulated response to amputation. Commonly used medications are often limited in their effectiveness and have significant side effects, making them unsustainable for many patients. As long as this phantom limb sensation is not uncomfortable or painful it does not need to be minded or treated. Phantom limb pain is a condition in which an amputee not only has phantom limb sensation after amputation, but sometimes suddenly feels pain in some part of the amputated hand or foot. There are many types of pain, most of the patients have cut-like pain and pins-and-needles pain first. In the later stage, the pain is more like burning pain or crushing pain. The duration of pain can be seconds or hours. Some patients may experience mild, transient phantom limb pain in the early post-amputation period, most of which may resolve on their own with a suitable prosthesis. If phantom limb pain still occurs frequently after wearing a prosthesis, the pain becomes increasingly worse and lasts longer, often accompanied by anxiety, depression, loss of appetite and insomnia, then promptly go to the hospital for treatment. Treatment: comprehensive treatment is needed 1. block and surgery: local pain point block of stump, somatic nerve block, as of stump exploration, spinal cord pain relief surgery; (spinal cord electrical stimulation, destruction of the dorsal heel of spinal cord into the medullary area, etc.) 2. medication; 3. psychotherapy; 4. minimally invasive neurointerventional treatment.