The main clinical manifestations of myofascial pain syndrome are: 1, pain or dull pain, pain in the form of tightness or heavy pressure, can occur in the lumbar, back, sacral, hip, leg, knee, plantar, neck, shoulder, elbow or wrist. 2.Ischemic pain: pain can be triggered by local cold or general fatigue, cold weather, waking up with pain during late night sleep, stiffness and pain in the morning, relieved after activity but often aggravated after long working hours or in the evening, and pain can be aggravated when inactive for a long time or overly active or even in bad mood. 3.Fixed pressure pain point: During physical examination, the patient is found to have tension, spasm, bulge, contracture or stiffness in one side or local muscles. The location of the pressure point is often fixed near the starting point of the muscle or the intersection of two groups of muscles in different directions, and painful hard nodes or painful muscle cords can be felt in the deep part of the pressure point. 4. There may be a history of local or adjacent injury, and the incidence is more frequent in women than in men. The diagnostic criteria for myofascial pain syndrome in the United States are: 1. There are fixed painful areas and pressure points on the attachment points of tendons or the muscle belly. Pressure on the painful points can trigger regional dispersed pain that is not distributed according to the nerve root sensation. 2.The pain worsens when the temperature decreases or when fatigue is present. 3.Treatment to increase blood flow to the muscles may reduce pain. 4.Exclude local occupying or destructive lesions. The treatment principles of myofascial pain syndrome are: 1. removing the cause: such as anti-rheumatoid, anti-inflammatory, loosening scars; 2. improving blood supply: exercise, massage, heat therapy (infrared, laser, cupping, acupuncture), etc. are effective but not healing, with a high recurrence rate; 3. anti-inflammatory and analgesic: can reduce symptoms and improve quality of life; 4. eliminating tenderness points: applying minimally invasive techniques to loosen local adhesions can prevent recurrence and aggravation of MPS. Long-term effect is good. Minimally invasive treatment techniques include Kawasaki block for acute pain, small needle separation for those with limited pain in the chronic phase, intensive warm mass needle loosening for those with widespread pain, radiofrequency thermal coagulation loosening for dangerous areas, etc. 5.Physical exercise: anti-gravitational muscle exercise. 6.Anti-depressant treatment.