The essence of muscle pressure pain is an aseptic inflammatory condition that manifests itself primarily as pressure, pain, and dysfunction in the affected area. Muscle pressure pain occurs in the muscles that innervate hyperactive or weight-bearing joints or in the muscles or ligaments that hold these joints together, especially at the point of attachment of the muscle or ligament to the bone. Prolonged and frequent repetition of a specific movement is a common cause of overload use. For the etiology and pathogenesis of muscle pressure pain, TCM treatment drugs should be based on regulating qi and relieving pain, activating blood stasis, and softening hardness and dispersion, supplemented by tonifying the kidney and strengthening the root, supporting the righteousness and dispelling evil, and improving the immunity of the body as the method of formulating. Then, the following is the content of the examination that needs to be done for muscle pressure pain. In order to eliminate whether the symptoms are due to other lesions or to exclude possible organic lesions, therefore, ECG, EEG, EEG topography, EMG, transcranial Doppler, CT head scan, rheumatic factor, anti-0, blood sedimentation, serum myoglobin, serum immunoglobulin G (IgG) and other tests are required. The peripheral blood leukocyte count was increased in the acute phase and normal in the stable phase. Serum CK and LDH were significantly increased during active disease. Electromyography suggests a combination of myogenic and neurogenic lesions, with increased spontaneous fibrillation potentials and positive phase spike waves. Muscle biopsy may reveal pathological changes such as myofiber degeneration, necrosis, muscle atrophy and regeneration, interstitial inflammatory cell infiltration, small vessel obstruction, and capillary endothelial proliferation. Hemoglobin may be decreased, and proteinuria suggests renal injury. Blood sedimentation may be increased, serum globulin may be increased, and rheumatoid factor may be positive in low titers.