Mold (fungi), like animals and plants, is a large community in the living world and is widely found in nature. Most grow in dark and humid environments, in the soil, sewers, carpets – even inside and outside our bodies are distributed in large numbers of mold, in human health, the body inside and outside the mold and the human body is a parasitic or symbiotic relationship, when the human physique declines, mold may multiply, leading to infectious diseases, in recent years found that sinus mycosis has increased trend. In addition to sinus local problems themselves, factors that can easily cause sinus mycosis are: 1, suffering from diabetes; 2, malignant tumors; 3, old age; 4, blood diseases; 5, after radiation therapy, chemotherapy; 6, after long-term use of broad-spectrum antibiotics or immunosuppressants. After the onset of sinus mycosis, patients will have general sinusitis symptoms such as nasal blockage and pus, and may have severe headache, and general antibiotic treatment is ineffective; in the case of Trichophyton infection, it will present malignant tumor-like aggressive, lesions develop rapidly, often with eye movement and visual impairment, severe cases with hemiplegia and deep mycosis of the whole body organs, which can be fatal. tumor-like destruction of the sinus bone wall can be seen on CT films, and sometimes There are characteristic calcified plaques, through the sinus endoscopy can take secretions to do smear examination to find mycobacterial mycelium to confirm the diagnosis. Treatment should be a combination of local and systemic therapy: 1, eliminate susceptibility factors, supportive therapy, systemic use of ketofurazole and other anti-mycotic agents; 2, active surgery, removal of lesions, fully open drainage of the sinuses; 3, the use of hormones discretionary for mycosis with metaplasia.