Urologic infectious diseases caused by Aspergillus singularis can be intervened with medications, lifestyle modifications, and other measures. Aspergillus singularis is the second most common Enterobacteriaceae causing urinary tract infections, second only to Escherichia coli, and can be intervened empirically with antimicrobial drugs such as cefotaxime and gentamicin, if the effect is not seen, it is recommended to perform a mid-epidemic urine culture to clarify the sensitive drugs and to adjust the medication regimen. If there is a combination of severe fever, urinary pain and other manifestations, ibuprofen and other antipyretic and analgesic drugs can be used as appropriate. At the same time, attention should be paid to the regulation of lifestyle, during the period of treatment need to quit smoking and alcohol, light diet, pay attention to drink more water, avoid spicy stimulating food intake; pay attention to rest and keep warm, so as to avoid the recurrence of new infections. The above drugs need to be used under the guidance of the clinician, unauthorized use of drugs is prohibited; the emergence of urinary urgency, urinary frequency, fever and other infectious manifestations, or suspected urinary tract infection, it is recommended to go to the hospital in a timely manner.