Nose flow yellow pus nose consider bacterial infection, combined with the duration of the disease may be associated with acute sinusitis, chronic sinusitis, fungal sinusitis secondary bacterial infection and other diseases, need to be targeted according to the cause of the treatment. 1. Acute sinusitis: the duration of the disease is relatively short, the patient may have a history of uptake in the early stage, the later complication of bacterial infection of the sinuses and lead to nasal discharge, nasal congestion, decreased sense of smell. The first recommendation: amoxicillin clavulanate potassium anti-infective treatment, with nasal spray glucocorticoids, promote mucus movement of pro-discharge agents, nasal irrigation and other symptomatic treatment. 2. Chronic sinusitis: the duration of the disease is generally longer, can be combined with nasal polyps, nasal septum deviation. It is first recommended to use macrolide antibiotics with nasal spray glucocorticosteroids and other symptomatic treatment. If the effect of drug conservative treatment is not good, surgery is recommended. 3. Fungal sinusitis secondary bacterial infection: patients with fungal sinusitis may have bacterial infection at the same time, which is manifested as pus flow, blood in the snot and so on. Combined with nasal endoscopy, sinus CT and other examinations, the need for early surgical treatment. Nose flow yellow thick nasal discharge, need otorhinolaryngology consultation, clarify the cause of the disease, follow the doctor’s instructions for treatment.