Smooth pale vinegar-white epithelial iodine test negative without coloration may indicate the presence of inflammatory or intraepithelial lesions of the cervix as seen on colposcopy. A smooth cervix on colposcopy means that the cervix is free of cervical masses and scarring.
Pale vinyl white is a description of the result of an acetic acid test, which may indicate the presence of mild epithelial lesions as normal squamous epithelium generally remains pink, and cells with an increased nuclear-to-plasmic ratio in normal or abnormal tissues may temporarily turn white.
A negative iodine test also suggests that the epithelium may be diseased. Normal cervical epithelium can be stained brown by iodine because it is rich in glycogen, whereas cervical columnar epithelium, immature metaplastic epithelium, keratinized epithelium, and atypical hyperplastic epithelium do not have glycogen, and therefore may not be colored by iodine.
In conclusion, it is considered that there may be inflammation or intraepithelial lesions in the cervix, leading to the above changes in the cervical epithelium, and it is recommended that timely medical treatment be standardized.