For thrombolysis, the main clinical term is the ability to dissolve the blood clot and improve this ischemic condition. For the top ten best drugs for thrombolysis, the first is alteplase, followed by urokinase. For these two drugs, patients are generally required to apply alteplase and urokinase within 4 and a half hours after admission to the hospital at the onset of the disease. The patient also does not have some contraindications for thrombolysis before alteplase and urokinase can be applied. The third thrombolytic drug is a clinical anti-platelet aggregation drug, such as aspirin or clopidogrel hydrogen sulfate, which can promote the dissolution of this thrombus, improve blood circulation, and prevent thrombus formation. Then there are good drugs for thrombolysis, clinically also can be bactrim, bactrim is a long-acting fibrin-lowering drugs, it can reduce serum fibrinogen, promote blood circulation, reduce the formation of thrombus. Then there are clinical anticoagulants that can also play a role in dissolving blood clots. Agatroban, a short-acting drug, is commonly used in clinical practice. In the acute stage, it is recommended to give the patient continuous sedation and monitor the coagulation results, and adjust the speed of medication according to the coagulation results. There are also some herbal medicines that have certain thrombolytic effects. For example, leeches and dilaudid can activate blood circulation, resolve blood stasis, and promote the circulation of blood vessels, which can also have a thrombolytic effect.