Patau’s syndrome is a disorder caused by abnormal chromosome development. In normal people, chromosome 13 is two, and children with Patau syndrome have one extra chromosome 13, so it is also known as trisomy 13. In addition to intellectual developmental disorders, children with Patau’s syndrome also have craniofacial developmental abnormalities, such as small head, prefrontal forebrain developmental defects, small eyeballs, wide and flat nose, cleft lip, cleft palate, and polydactyly (toes). Developmental anomalies of internal organs, atrial and ventricular septal defects, polycystic kidneys. Pregnant women can use medical methods such as non-invasive DNA testing through blood collection to help diagnose any fetal chromosome abnormalities.