Whether or not you can rub Vitamin A acid on your legs with florid spots is related to the cause of the florid spots. If it is a keratinized plaque, such as psoriasis, you can rub Vitamin A acid, if it is a pigmentation loss plaque, such as vitiligo, Vitamin A acid is generally ineffective. 1. can be rubbed: Vitamin A can promote epithelial cell proliferation, inhibit keratinocyte proliferation and differentiation, so that the over-keratinized skin recovery, for keratinized plaques, such as psoriasis, lichen planus, etc., has a certain effect on the abatement. 2. Can not be rubbed: melanocytes are damaged or missing, such as vitiligo, etc., or vascular lesions, such as anemia nevus, etc., causing skin patches, rubbing Vitamin A acid generally has no obvious effect, and is not recommended. If there are patches on the legs, it is recommended to go to the dermatology department for examination, to clarify the cause of the disease, and actively treat it to avoid affecting the quality of life.