Cervical spine pain at night sleep are afraid to turn over may be caused by the stiffness of the neck muscles, spasm or cervical spondylosis and other reasons, the treatment mainly includes physical therapy and medication and so on. 1. Physical therapy: If the pain is caused by stiffness and spasm of the neck muscles, firstly, you can replace a sponge pillow with a suitable height to have a good support and protection for the cervical vertebrae, and secondly, you can choose physical therapy such as heat therapy, massage, traction and microwave to accelerate blood circulation of the neck muscles, loosen the tense muscle fascia, and alleviate the fatigue and stiffness of the muscles. 2. Medication: Patients with cervical spondylosis or more obvious pain symptoms can be treated with medication, such as non-steroidal anti-inflammatory drugs (NSAIDs) such as celecoxib and ibuprofen; myorelaxants such as epirubicin hydrochloride tablets and clotrimazole tablets to relieve muscle spasms; and decongestants such as mannitol and heptaphyllum saponin sodium to reduce oedema and compression. The above drugs need to be used under the guidance of a doctor, avoid self-medication. If the pain symptoms are not relieved, or accompanied by other symptoms, you should go to the hospital in a timely manner, to clarify the cause and give targeted treatment.