Liver lesions with pedunculated feet, most commonly seen in patients in the decompensated stage of cirrhosis, are mainly caused by hypoalbuminemia, which is usually more serious and requires active treatment. Due to the metabolic dysfunction of the liver, patients in the decompensated stage of liver cirrhosis have a decreased ability to synthesize albumin, and may have varying degrees of hypoalbuminemia, which causes a decrease in the plasma colloid osmotic pressure, the formation of a large amount of ascites and pressure on the blood return to the lower extremities, leading to the symptoms of edema in the feet. Liver lesions caused foot swelling patients, indicating that the liver has been damaged more seriously, in addition to the symptoms of foot swelling, but also may be secondary to upper gastrointestinal bleeding, hepatic encephalopathy and other serious complications. Long-term or even lifelong treatment with oral antiviral drugs such as entecavir and tenofovir is required. It is also necessary to correct hypoalbuminemia by intravenous supplementation of human albumin and fresh plasma to increase the plasma colloid osmotic pressure and reduce the symptoms of swollen feet. Patients with swollen feet caused by liver lesions should consult the doctor in time and actively cooperate with the doctor’s treatment. At the same time, usually should avoid standing for a long time, can be appropriate to elevate the lower limbs, is conducive to promote the lower limbs blood return, reduce the symptoms of swollen feet.