Epididymal distension in men may be due to prolonged absence of ejaculation, but in addition to this, it may also be due to prostatitis, epididymitis and other diseases. 1. Long time without ejaculation: long time without ejaculation, the spermatic cord muscle is in too tense state, and then again erection is easy to cause genital congestion and edema, thus causing epididymal swelling. 2. Prostatitis: when prostatitis aggravates and causes edema and congestion of the prostate gland, the pressure to the pelvic floor area will radiate to the surrounding tissues, including the scrotum, epididymis and other tissues, which will easily cause epididymal distension and pain. 3. Epididymitis: it is an inflammation that occurs in the epididymis, and long-term inflammation stimulation will cause epididymal distension and pain, which is also a common symptom of the disease. The causes of epididymal distension and pain in men are many, so avoid taking medication without analyzing the cause of the disease. It is necessary to consult a doctor in a timely manner and conduct differential analysis through physical screening, routine urinalysis and imaging to understand the cause before proceeding with treatment.