Psoriasis is a chronic and recurrent disease, and many patients need long-term medical treatment. There are many topical drugs for the treatment of psoriasis, which should not be used arbitrarily, and the following points should be noted: 1. Before applying topical drugs, it is advisable to wash away the scales with hot water soap in order to make the drugs work better; 2. In the acute phase of psoriasis, when the inflammation of the lesions is obvious, it is not advisable to use topical drugs with strong irritation, so as not to stimulate the occurrence of erysipelas, and stronger drugs can be used in the stable phase. 3.When the skin lesions are extensive, the use of topical drugs in a large area will cause poisoning due to excessive absorption. Therefore, the concentration of the selected drugs should be reduced, and different drugs should be applied in different areas to reduce the excessive absorption of a single drug, especially do not use hormone preparations over a large area. 4, some topical drugs are likely to cause irritation and dermatitis, these drugs should be used with special caution on the face and other places, not for parts close to the mucous membrane, such as the perineum, around the anus, etc. 5, underarm, groin and other friction parts and face are more sensitive to hormones, easy to produce skin atrophy, pigmentation, capillary dilation, etc., so in these parts of the application of drugs should be less adverse reactions to the use of topical hormones. 6. Infection should be controlled first before treatment. When there is exudation, it should be treated as acute or subacute dermatitis.