Cranial defect is a common disease in neurosurgery, and the danger of cranial defect is still very big. One is the lack of protection, may cause secondary damage, and even directly threaten the safety of brain tissue, resulting in serious consequences; another is because the defect of the skull will cause some dysfunction of the intracranial nervous system, resulting in some uncomfortable symptoms, which is often referred to as cranial defect syndrome; there is also an important harm, that is, it may be on the patient’s psychology and spirit of the damage, the patient may have a great sense of inferiority. Another important harm is that it may cause great damage to the patient’s psychology and spirit, and the patient may have a great inferiority complex. Therefore, after the occurrence of cranial defects, cranial bone repair should be carried out in a timely manner. Some patients ask about the symptoms of thermal expansion and contraction after cranial bone repair. This is related to the material used for cranial bone repair. At present, most of the hospitals in the clinical widely used cranial bone repair material is titanium alloy titanium mesh material, this metal material has a certain coefficient of thermal expansion and contraction, may be due to changes in the external temperature caused by thermal expansion and contraction of the phenomenon, resulting in a lot of discomfort; at the same time titanium mesh of this metal material, insulation is not good, the outside world of the hot and cold environment, the temperature of the material may be directly affect the temperature of the material, which affects the internal temperature, also produces many symptoms of the cranium. Environmental temperature, will also produce a lot of discomfort; at the same time, titanium mesh material also has some other problems, such as postoperative infection and rejection, deformation, wear and tear of the scalp, resulting in the exposure of the material, affecting the ct nuclear magnetic examination and so on. Therefore, it is not recommended to use titanium mesh material for skull repair. The current clinical use of new polyether ether ether ketone peek material for cranial bone repair, and constantly improving and upgrading technology, material optimization design, and the introduction of cosmetic plastic concept. Thus, the comprehensive peek cranial bone repair plastic surgery, not only can complete a good cranial bone repair, but also to ensure tissue activity, to ensure the integrity of the nerve function and the shape of the skull in the proportionality of the beautiful aspects of the good, to achieve anatomical completeness, functional perfection, the overall unity of the appearance of the beautiful, and received the majority of patients and families of the praise and recognition.