Due to the large individual differences, there is no most effective way to remove spots on the face. Physical methods and medication can be taken according to different situations, and common spots include freckles, chloasma, age spots, and so on. 1. Freckles: related to congenital factors or ultraviolet irradiation, in addition to avoiding ultraviolet irradiation, 30%~35% trichloroacetic acid solution can be used to spot-coat the spots, so as to locally corrode the spots, and laser or freezing can also be taken as a method to remove them. 2. Melasma: it has a great relationship with sunshine, therefore, on the basis of good sunshine protection, it can use hydroquinone decolorant and other medication as prescribed by doctor, and also choose azelaic acid cream, vitamin A acid and other medication, and if necessary, it can take strong pulsed light or Nd:YAG laser with large light spot and low energy laser. 3. Age spots: mainly due to skin aging and long-term sun exposure, generally choose physical therapy such as freezing, laser and other methods. It is recommended to go to regular hospitals for consultation, clear diagnosis and symptomatic treatment to avoid delaying the condition. Drugs should be used according to the doctor’s prescription.