Yellowing of the whites of the eyes with blood due to visual fatigue, blepharospasm, chronic conjunctivitis, etc. is usually not important. Yellowing of the whites of the eyes caused by systemic diseases is important and needs to be treated as soon as possible. The most common clinical causes of yellowing of the whites of the eyes with blood include: visual fatigue caused by prolonged close-up use of the eyes, blepharospasm due to conjunctival degeneration caused by long-term ultraviolet irradiation or environmental stimuli such as sand and wind, chronic inflammation of the conjunctiva of the eyes and so on, which will not have an impact on the eyesight, and therefore, generally does not matter. Rare clinical causes of yellowing of the whites of the eyes with blood mainly refers to systemic diseases, such as: because of hepatobiliary diseases caused by scleral yellowing with red blood, it is important, need to go to the liver and gallbladder internal medicine and surgery in a timely manner to the doctor for treatment.