Taking Irbesartan Hydrochlorothiazide Tablets may cause a decrease in glucose tolerance and cause an increase in blood sugar. Irbesartan Hydrochlorothiazide Tablets is a combination of angiotensin antagonist and diuretic antihypertensive drug for primary hypertension, used in patients whose blood pressure cannot be effectively controlled by Irbesartan or Hydrochlorothiazide alone. Irbesartan Hydrochlorothiazide Tablets cause elevated blood glucose is hydrochlorothiazide, hydrochlorothiazide is a thiazide diuretic, which may reduce glucose tolerance and cause elevated blood glucose. Common adverse reactions to Irbesartan Hydrochlorothiazide Tablets include dizziness, fatigue, nausea, vomiting, and abnormal urination. In addition, this product should be contraindicated in people who are allergic to this product or to other sulfonamide derivatives, and it is not recommended for use during the first trimester of pregnancy. The use of Irbesartan Hydrochlorothiazide Tablets needs to be under the supervision of a doctor and should not be used on its own.