Common disorders that cause nipple pressure pain in eight-week-old girls include breast development and mastitis, which need to be treated according to the cause. Puberty in girls usually starts around the age of 9 to 10, and breast development is an important sign of pubertal development. It is generally recognized that breast development in girls before the age of eight is likely to be precocious puberty. Precocious puberty is harmful to children’s psychological behavior and physical development. 1.8-year-old girls nipple pressure pain may be caused by breast development, specific can be diagnosed as precocious puberty, need to consult a clinician according to the child’s development indicators for comprehensive judgment. If the diagnosis of precocious puberty is confirmed, treatment with drugs that inhibit the initiation of the gonads (e.g., leuprolide, etc.) may be needed. 2. If the child has sore nipples, fever, redness and swelling of the breasts, mastitis may be the cause. Antibiotic treatment (e.g., amoxicillin, etc.), antipyretic treatment (e.g., acetaminophen, etc.), and localized warm compresses are needed. Different diseases require different treatments. It is recommended to go to the hospital for a complete examination and treatment after a clear diagnosis, and the above medications should be used according to the doctor’s instructions.