Cervical intraepithelial neoplasia grade III, which refers to highly squamous lesions in the cervical epithelium, suggests possible precancerous lesions or carcinoma in situ, and belongs to the early stage of cervical cancer, with a higher risk of developing into cervical invasive cancer at a later stage. Patients need timely surgical treatment and can choose different treatment options according to their age and reproductive requirements: 1. with reproductive requirements: young, age-appropriate women with strong reproductive desire are recommended to undergo cervical loop electrosurgery or cold knife cervical conization surgery to remove local lesions and send them for pathological examination after surgery to determine whether there are abnormal cells at the cut edge or whether there is invasive cervical cancer, and decide whether to follow up with subsequent treatment; 2. 2. No reproductive requirements: Women who are older, do not have strong reproductive will and have combined indications for surgery for other benign gynecological diseases, extra-fascia total hysterectomy is feasible. Generally speaking, the onset of cervical intraepithelial neoplasia grade III is associated with persistent high-risk HPV infection, unclean sexual life, premature sexual life, and smoking. Therefore, it is important to maintain good lifestyle habits after surgery and follow medical advice for regular review to detect recurrence and deal with it early.