Glioblastoma grade IV is currently considered to have a poor prognosis, with patient survival ranging from about one to two years, depending on the individual. Glioblastoma grade IV belongs to the more serious type in the WHO classification, where the tumor has extensively invaded the peripheral nerves and is growing very fast. Due to the compression of the tumor, patients may experience headaches, vomiting and other symptoms related to increased intracranial pressure. Due to the metastasis and spread of glioblastoma grade IV, the survival period is generally around one to two years, but this is only an average survival period, each person’s situation is different, the specific survival period varies from person to person, and is related to the size of the tumor, the spread of the range, and the patient’s state, and so on. It is recommended that patients with glioblastoma should seek medical treatment as early as possible and standardize the treatment under the guidance of doctors in order to maximize the prognosis.