Serum homocysteine is a metabolite of amino acids in the body. Serum homocysteine is a metabolite of amino acids in the body that normally provides the body with methyl groups and has antioxidant properties. Increased serum homocysteine levels are detrimental to the human body and may increase the risk of atherosclerosis, resulting in a significantly higher incidence of cardiovascular disease. Patients with hypertension are prone to elevated serum homocysteine, and the presence of both increases the risk of atherosclerosis. Serum homocysteine levels can be measured by blood tests to assess the risk of cardiovascular disease, and in severe cases oral treatment with B vitamins and folic acid tablets is required. Patients suspected of having elevated serum homocysteine levels can have blood tests to find out the exact level and be treated under the supervision of a physician.