Knee pain and swelling may be caused by trauma or inflammatory lesions in the knee, and the treatment needs to be analyzed specifically, mainly including physical therapy, medication and surgical treatment. 1. Trauma: If the patient suffers from trauma, resulting in knee fracture, meniscus injury, ligament tear, etc., the clinic can be cold compresses, brakes and other conservative treatment to relieve pain and swelling symptoms. For fracture, meniscus injury and ligament injury patients need to cooperate with surgical treatment to restore the integrity and stability of the joint structure. 2. Inflammatory lesions: If the patient’s knee has inflammatory lesions, such as osteoarthritis of the knee joint, synovitis, etc., the symptoms of pain and swelling will occur. Patients can relieve the symptoms through physical therapy, hot compresses and other ways. At the same time, medication is needed to control the symptoms, such as ibuprofen extended-release capsules, celecoxib tablets, etc. In severe cases, artificial joint replacement surgery is needed. The above drugs need to be used under the guidance of a doctor, it is recommended that patients with symptoms of knee pain and swelling, timely medical confirmation of the cause of the disease for targeted treatment.