Hand numbness is usually associated with cerebrovascular disease or diabetes mellitus, chest tightness, shortness of breath, dyspnea is usually associated with cardiopulmonary diseases, if they appear together, the greatest likelihood is still cardiopulmonary disease. First of all, when the cerebrovascular ischemia, oxygen supply is insufficient, can lead to numbness of the extremities, or diabetes mellitus more than ten years of patients, when the blood glucose control is poor will also appear glove sign phenomenon. When hand numbness is accompanied by chest tightness, shortness of breath, dyspnea, it is necessary to do cardiac function measurement and pulmonary function measurement test to see if it is pulmonary heart disease, angina pectoris, myocardial ischemia and other disorders caused by the above symptoms. If the diagnosis can be made, immediate symptomatic treatment is recommended, which can be given to improve myocardial blood supply, reduce cardiac function metabolism, asthma, oxygen inhalation and other treatments.