Stage IIB is generally an intermediate stage. Stage IIB generally belongs to the middle stage of malignant tumors, for this type of patients need to be based on the patient’s pathological type as well as the systemic condition and even the genetic test results to guide the patients whether they need the next step of adjuvant therapy can further improve the patient’s prognosis and enhance the patient’s therapeutic efficacy. Stage IIB patients have a certain risk of recurrence and metastasis, so after the end of treatment must pay attention to timely follow-up, early detection, early treatment, for patients who can not be surgically resected, should adopt a relatively conservative treatment, and wait for the patient’s general physical condition to ease before choosing the appropriate treatment program, and strive to improve the quality of life. Stage IIB patients should be treated aggressively in order to improve the survival rate.