Bone marrow aspiration is relatively safe in general, complications may occur, mainly including infection of the puncture site, which may be caused by the entry of bacteria due to the lack of strict aseptic operation, and bleeding at the puncture site and the formation of a local hematoma, which may be caused by bleeding of blood vessels due to injuries to small subcutaneous blood vessels at the time of puncture. In addition, it may also be due to the patient has hemophilia, coagulation function is abnormal, in the puncture can not stop bleeding, it will form bleeding, and the puncture area has a lot of skin nerves distribution, in the puncture there is a possibility of damage to the skin nerves, it will cause local small patchy skin sensory abnormalities.