Epithelioid trophoblastic tumors are cancers that are trophoblastic and difficult to diagnose.
Epithelioid trophoblastic tumor (ETT) commonly develops at the age of 15-66 years, and is rare in postmenopausal women. It originates from chorionic intermediate trophoblastic cells, has a specific tissue type and immunological phenotype, and is very rare in gestational trophoblastic neoplasms (GTNs), which account for 1.39% to 2% of GTNs.
ETT is a low-grade malignant tumor similar to placental site trophoblastic tumor (PSTT), which grows more slowly but is highly aggressive and usually has a poor prognosis, with a mortality rate of about 10% to 13%.
The disease lacks specificity and is relatively rare, preoperative diagnosis is very difficult, the diagnosis must rely on pathology, the most effective treatment is surgical treatment, and currently the clinical treatment is mostly individualized according to the patient.