Elevated blood β2-microglobulin cannot clearly diagnose specific diseases, and common clinical causes include renal impairment, lymphoproliferative diseases, autoimmune diseases and so on.
1. Renal function impairment: blood β2 microglobulin measurement is often used to monitor renal function, elevated blood β2 microglobulin often indicates a decline in glomerular filtration function, common diseases include acute and chronic nephritis, chronic renal failure and so on.
2. Lymphoproliferative diseases: blood β2-microglobulin is obviously elevated in patients with multiple myeloma and chronic lymphatic leukemia, in addition, blood β2-microglobulin is also elevated in patients infected with human cytomegalovirus, hepatitis B virus and HIV virus.
3. Autoimmune diseases: in the active phase of systemic lupus erythematosus, blood β2 microglobulin is obviously elevated, and some studies have shown that 50% of patients with rheumatoid arthritis have elevated blood β2 microglobulin.
When the blood β2 microglobulin is elevated, it is necessary to consult a doctor in time, to clarify the specific cause of the disease through detailed examination, and to carry out causative treatment under the guidance of a physician.