Irregular menstruation in a 50-year-old woman is usually caused by perimenopause, and the treatment includes follow-up observation, medication, scraping the uterus, and oral antiemetic drugs. 1. If the amount of menstruation is reduced, but not accompanied by other symptoms, then generally do not need special treatment, follow-up observation. 2. If abnormal menstruation is accompanied by hot flashes, excessive sweating, irritability, etc., then you can go to the hospital in time to see if you need to follow the doctor’s instructions to use medication to treat the manifestations of menopausal syndrome. 3. If the amount of menstruation is abnormally increased, then we also need to be vigilant about whether there are organic lesions, etc., the need for timely intervention, whether it is necessary to scrape the uterus, oral antiemetic drugs, etc.. In short, 50-year-old irregular menstruation may be perimenopausal normal change, may also be caused by disease, need to go to the hospital to clarify the cause of the disease, give symptomatic treatment.