Long-term abdominal pain requires endoscopy, laboratory monitoring such as Hepatitis B two half, liver function, urea breath test, abdominal ultrasound and other imaging tests. 1. Endoscopy: Gastroscopy is the most common and accurate examination method for stomach and duodenum, endoscopy can observe mucosal lesions and also take biopsy; capsule endoscopy can be chosen for those who suspect lesions in small intestine. 2. Laboratory tests: Hepatitis B two halves, 13C or 14C urea breath test to detect Helicobacter pylori, blood sampling to detect serum serum protein, cholesterol, bilirubin and so on to assess liver function. 3. Imaging tests: such as ultrasound can detect lesions in substantial organs. Prolonged abdominal pain should go to the hospital immediately, under the guidance of professional doctors to choose the appropriate examination and take reasonable measures to improve the quality of life.