Thermoregulatory disorders are fevers that result from abnormalities in the thermoregulatory center due to central nervous system pathology. The basic center of thermoregulation is the hypothalamus. Animals in which the forebrain above the hypothalamus is removed, i.e., “hypothalamic animals,” maintain near-normal thermoregulatory function. Animals with all forebrain above the midbrain (including the hypothalamus) removed are unable to maintain a relatively stable body temperature. Thermoregulation refers to the process by which temperature receptors receive internal and external environmental temperature stimuli and cause changes in the activities of endocrine glands, skeletal muscles, skin vessels, sweat glands and other tissues and organs through the activity of the thermoregulatory center, thus adjusting the process of heat production and heat loss to keep body temperature at a relatively constant level. It is a higher level regulatory function acquired by animals in the long-term evolutionary process. The center of thermoregulation is located in the hypothalamus. Traditional physiology believes that there is a heat dissipation center in the anterior hypothalamus and a thermogenic center in the posterior hypothalamus, and that there is a reciprocal inhibition between the two centers, thus maintaining the relative stability of body temperature. Thermoregulatory disorders are examined by: poor response to antipyretic and analgesic drugs and effective physical cooling. Drugs regulate body temperature by: changing the mechanism of temperature regulation, drug metabolic heat, hypersensitivity reactions, etc. Check the urine, blood endocrine problems, see how the liver and kidney function, any abnormal medical history, family history. Body temperature measurement Body temperature measurement is a common test used to diagnose diseases, and there are three types of temperature measurement: oral, axillary and anal. In most cases, the axillary temperature is used to measure the temperature, rarely the oral temperature, and rarely the anal temperature (the normal value is 36.5°-37.7°). Each time with the axillary temperature measurement, the middle can not be interrupted, must have been stepped up thermometer to 10 minutes to be the most accurate.