Esophageal leukoplakia is a rare disease that occurs mainly in the mucous membrane of the oral cavity or vulva, and the symptoms of this disease are mostly seen in male patients over 40 years of age. If the patient has taken a lot of antibiotics, the patient needs to be reviewed after 2-3 weeks of treatment. If the disease is caused by other reasons, it is recommended that the patient can be reviewed once a month. It is advisable to go to the hospital regularly for review and to pay attention to the diet during the treatment period. Do quit smoking, alcohol, spicy, greasy, try to remove the trigger, and do not overeat, so as not to cause irritation to the esophagus aggravate the disease, or lead to recurrence of the disease.