The first thing you need to do is to go to the hospital and have a relevant examination to clarify the cause of the inability to urinate and then further treat the cause. 2. If an acute infection occurs, there is urethral mucosal edema, pain and the patient is unable to urinate. Then it is recommended to give anti-infective drugs and wait for the infection and edema to reduce before observing urination.3. If a man, over 50 years of age, suddenly has symptoms of difficulty in urination, it is important to consider whether urinary retention is caused by prostatic hyperplasia. It is recommended that a urinary ultrasound and residual urine examination be performed. If prostatic hyperplasia does exist and there is a large amount of urine retention in the bladder with excessive residual urine, it is recommended that indwelling catheterization be given. The catheter is left in place for 2-3 days, during which time oral medication for prostatic hyperplasia is administered before the catheter is removed and urination is observed. 4. If a patient with a history of stones is unable to urinate, it is important to consider whether the inability to urinate is due to stones obstructing the urethra. It is recommended to perform ultrasound or CT examination of the urinary system to clarify the presence of stones and the specific part of the stone, and to give treatment such as extracorporeal shock wave lithotripsy, temporary indwelling catheterization, and surgical removal of the stone, at which time urination can be restored.