Myocardial abscess is one of the main clinical symptoms of dilated cardiomyopathy (cardiomyopathy (DDM)), a group of pathologies that result in progressive cardiac dysfunction due to structural changes in the lower portion of the heart’s chambers (i.e., ventricles) and impaired function of the myocardial wall. Its clinical manifestations include heart enlargement, arrhythmias, embolism and heart failure. The causes are generally related to viral infections, autoimmune reactions, genetics, drug toxicity and metabolic abnormalities. (According to the pathology, it can be divided into dilated cardiomyopathy, hypertrophic cardiomyopathy and restrictive cardiomyopathy, etc.). Prevention and treatment of myocardial abscess: 1, general treatment: rest, use sedatives if necessary, low-salt diet in heart failure; 2, prevention and treatment of arrhythmia and cardiac insufficiency; 3, anticoagulant therapy for those with history of embolism; 4, thoracentesis and aspiration for those who have a large amount of pleural effusion; 5, artificial heart surgery or heart transplantation may be considered in severe patients, and CRT therapy may be performed; 6, symptomatic and supportive therapy.