Mycoplasma pneumoniae is an acute respiratory infection. Due to these predisposing factors such as exposure to cold, rain, and decreased resistance, Mycoplasma pneumoniae invades the body and causes an inflammatory reaction of congestion, edema, and exudation of inflammatory substances from the mucous membranes of the lungs. It is usually seen in acute infectious episodes and should be treated with symptomatic and etiologic treatment. Blood tests and serum markers related to Mycoplasma pneumoniae can be performed, and respiratory secretions can be taken to detect Mycoplasma pneumoniae DNA for a definitive diagnosis. For irritating cough, cough and phlegm medication can be used, such as fenugreek syrup and carbocysteine oral solution. Anti-mycoplasma infections can be treated with macrolides such as erythromycin and azithromycin.