Toothache and calf pain are two separate symptoms that are generally not related to each other. Toothache may be caused by caries, pulpitis, apical periodontitis, and calf pain may be caused by lumbar disc herniation, sciatica, trauma, etc., as follows. 1. Toothache: when deep caries occurs, when food is embedded in the cavity, it will cause toothache; when pulpitis occurs, the affected tooth will have spontaneous pain, night pain and other characteristic pain; when apical periapical inflammation occurs, the affected tooth will have occlusal pain and knocking pain. 2. Calf pain: when herniated disc occurs, there is extrusion and stimulation to the nerve root, which may produce pain in the calf area; when sciatica occurs, the sciatic nerve is compressed, which produces radiating pain in the calf area. There are also other possibilities such as trauma. Toothache and calf pain may have other causes, it is recommended to go to the hospital in time, with the help of the doctor for targeted treatment.